Salesforce Tower, formerly known as the Transbay Tower, is a 1,070-foot (326 m) office skyscraper in the South of Market district of downtown San Francisco. It is located at 415 Mission Street between First and Fremont Streets, next to the Transbay Transit Center site. Salesforce Tower is the centerpiece of the San Francisco Transbay redevelopment plan. The plan contains a mix of office, transportation, retail, and residential uses. This was the last building designed by César Pelli to be completed in his lifetime.

Upon its completion in 2018 it became the tallest skyscraper in the San Francisco skyline, with a top roof height of 970 feet (296 m) and overall height of 1,070 feet (326 m), surpassing the 853 feet (260 m) Transamerica Pyramid. It is also the second-tallest building west of the Mississippi River after the 1,100 feet (335 m) Wilshire Grand Center in Los Angeles, though the Salesforce Tower is taller when Wilshire Grand Center’s decorative spire is excluded, but has a shorter roofline than Los Angeles’ U.S. Bank Tower.